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A human mitochondrial genome database. A compendium of polymorphisms and mutations of the human mitochondrial DNA.


MitoData is a unique multi-national database holding clinical, biochemical and molecular genetic data on human mitochondrial diseases.


Mamit-tRNA is a compilation of mammalian mitochondrial tRNA genes. It contains presently 3064 tRNA gene sequences from 150 fully sequenced genomes available on GenBank database (NCBI). This is the follow-up of our previous investigation on a smaller set of mammals which allowed to highlight peculiar and specific structural characteristics of mammalian mitochondrial tRNAs (Helm M. et al. RNA. 6, 1356-79 (2000)).
Mamit-tRNA, to be updated regularly, is expected to serve as basis towards the deciphering of structural features of mammalian mitochondrial tRNAs and a helpful tool in the frame of human diseases linked to point mutations in mitochondrial tRNA genes.


Mitochondrial Proteome
Database for mitochondria-related genes, proteins and diseases
The aim of this database is to provide a comprehensive list of mitochondrial proteins of yeast, mouse, Arabidopsis thaliana, neurospora and human. Datasets relevant to the study of the mitochondrial proteome are integrated and accessible via search tools and links. They include computational predictions of signalling sequences and summarize results from proteome mapping, mutant screening, expression profiling, protein-protein interaction and cellular sublocalisation studies. Predictive scores (score based on support vector machine prediction) are given and are calculated using the integration of the included datasets and annotated reference sets of mitochondrial proteins.

Welcome to the Organellar Genome Retrieval system at McMaster University.
OGRe is a searchable relational database which currently contains the complete mitochondrial genome sequences of 1015 metazoan organisms.
In addition to gene sequences, OGRe also contains information on gene order and codon usage.


Human Mitochondrial Genome Database

The GiiB-JST mtSNP (mitochondrial single nucleotide polymorphism) database provides information related to the functional differences among mitochondrial SNPs. This web site is useful for identification of mtSNPs associated with age-related conditions such as longevity, Parkinson's disease, and Alzheimer's disease, as well as those related to energy metabolism such as obesity, thinness, and type-2 diabetes, or to atherosclerosis. The main part of this mtSNP database includes the entire mitochondrial genome sequences of individuals belonging to 7 different groups, with 96 individuals in each group, namely, centenarians, patients with Parkinson's disease, patients with Alzheimer's disease, young obese males, young non-obese males, and type-2 diabetes patients with or without severe vascular involvement.

Mitochondrial Protein database
The Human Mitochondrial Protein Database (HMPDb) provides comprehensive data on mitochondrial and human nuclear encoded proteins involved in mitochondrial biogenesis and function.

Mitochondrial DNA Control Region Database
The EMPOP Database aims at the collection, quality control and the searchable presentation of mtDNA control region haplotypes from all over the world. The EMPOP project is a scientific collaboration between the Institute of Legal Medicine (GMI), Innsbruck Medical University and laboratories performing mtDNA research.

GOBASE is a taxonomically broad organelle genome database that organizes and integrates diverse data related to mitochondria and chloroplasts. GOBASE is currently expanding to include information on representative bacteria that are thought to be specifically related to the bacterial ancestors of mitochondria and chloroplasts

This database is dedicated to the nuclear genes specifying the enzymes, structural proteins, and other proteins, many still not identified, involved in mitochondrial biogenesis and function.

Genome Project

Phytophthora infestans Mitochondrial Genome Project
web: www.

Tomato Mitochondrial Genome

The Dictyostelium Sequencing Project Mitochondrial DNA

Fungal Mitochondrial Genome Project (FMGP)

Tetrahymena thermophila Genome Project

Related Resources

Sequence data and related info (NCBI Organelle Genome Resources)

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